DETECTION OF HELICOBACTER PYLORI IN BLOOD AND STOOL SAMPLES: A COMPARATIVE STUDY OF ANTIBODY-BASED TESTS

Abstract

Helicobacter pylori infection is a significant global health challenge. Accurate diagnosis is crucial for effective management and treatment. Currently, various diagnostic methods are available, including antibody-based tests on blood and stool samples. However, the reliability and efficacy of these tests remain uncertain. This study focused on the detection of H. pylori in blood and stool samples using antibody-based tests. A total of 200 stool and blood samples were collected and screened for HP using an antibody-based assay. The study revealed that the Blood antibody test (48.90) significantly (p≤ 0.05) detected H. pylori more than the stool antibody test (19.40%), and the detection was mostly seen among female patients, patients of age 45 years and above, traders and those patients with no formal education. There was a significant (p≤ 0.05) increase in the detection of H. pylori among those patients who had stomach ulcers, heartburn, chest pain, epigastric pain, abdominal pain, inflammation and constipation, compared to healthy individuals. Therefore, the study has shown that H. pylori was significantly detected in blood samples than in stool samples using antibody-based tests, and sociodemographic factors and medical history of the patients influenced the test